Directed Evolution At Biology Glossary
What is it? This term is used in two ways. (i) A laboratory process using mechanisms of natural selection to produce mutants adaptated to defined environmental challenges. This approach can be used to produce adaptions in single molecules, such as a RNA molecule or an enzyme. Since chemical reaction can occur very fast, multiple generations of molecules can be produced quickly. Microorganisms such as bacteria can also reproduce quickly, allowing multiple generations of selection in a short period of time. This approach has been used to produce novel enzymes with industrial and biomedical applications, and to produce bacteria with potential bioremediation applications. (i) The concept that under certain stressful conditions, there is a selection for those mutational changes that favor survival. This controversial concept, also called adaptive evolution, is essentially a molecular version of Lamarkian evolution.Bio Definition Added By: Dylan
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