Colicin
What is it? A polypeptide secreted by bacteria which inhibit or prevent the growth of related bacteria which lack the corresponding colicin immunity proteins. Colicins are encoded by a group of naturally occurring plasmids first found in E. coli (e.g., the Col E1 plasmid). Colicins kill other bacteria by a variety of mechanisms depending on the type of colicin -- some colicins block protein synthesis, some colicins induce the degradation of chromosomal DNA, some colicins form transmembrane holes in the cytoplasmic membrane, etc.Added By: Benjamin
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