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Gene Conversion At Biology Glossary

What is it? A meiotic process of directed change in which one allele directs the conversion of a partner allele to its own form. In asci of Ascomycete fungi a 4:4 ratio of alleles is expected after meiosis, yet 6:2 and 5:3 ratios are sometimes observed. A model of recombination, produced by Holliday, suggests that gene conversion may be explained by repair of heteroduplex DNA.

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